KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NCL
All Species:
29.39
Human Site:
T214
Identified Species:
64.67
UniProt:
P19338
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19338
NP_005372.2
710
76614
T214
E
E
E
A
M
E
T
T
P
A
K
G
K
K
A
Chimpanzee
Pan troglodytes
XP_516145
1006
108719
T485
E
E
E
A
M
E
T
T
P
A
K
G
K
K
A
Rhesus Macaque
Macaca mulatta
XP_001116949
938
100743
T442
E
E
E
A
M
E
T
T
P
A
K
G
K
K
A
Dog
Lupus familis
XP_850477
699
75739
T200
E
E
E
A
M
E
T
T
P
A
K
G
K
K
A
Cat
Felis silvestris
Mouse
Mus musculus
P09405
707
76705
T220
E
E
E
V
M
E
I
T
T
A
K
G
K
K
T
Rat
Rattus norvegicus
P13383
713
77129
T221
E
E
E
V
M
E
I
T
P
A
K
G
K
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509329
631
67414
T217
E
E
E
P
V
K
E
T
L
G
K
R
K
K
E
Chicken
Gallus gallus
P15771
694
75622
T197
E
D
E
A
M
D
T
T
P
A
P
V
K
K
P
Frog
Xenopus laevis
P20397
651
70177
S207
D
E
E
E
Q
Q
G
S
A
K
R
K
K
E
M
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797746
400
43419
E51
S
E
E
S
S
E
D
E
V
E
V
P
V
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P27476
414
44517
E65
S
S
S
S
S
D
S
E
S
S
S
S
S
S
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.3
74.7
91.6
N.A.
83.9
84.2
N.A.
65.6
63.2
55.6
N.A.
N.A.
N.A.
N.A.
N.A.
24
Protein Similarity:
100
70.4
75.4
94.9
N.A.
90.1
90.4
N.A.
73.9
76
68.4
N.A.
N.A.
N.A.
N.A.
N.A.
32.8
P-Site Identity:
100
100
100
100
N.A.
73.3
80
N.A.
46.6
66.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
100
100
N.A.
73.3
80
N.A.
60
80
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
46
0
0
0
0
10
64
0
0
0
0
37
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
0
0
19
10
0
0
0
0
0
0
0
0
% D
% Glu:
73
82
91
10
0
64
10
19
0
10
0
0
0
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
10
0
55
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
19
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
10
0
0
0
10
64
10
82
82
10
% K
% Leu:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% L
% Met:
0
0
0
0
64
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
55
0
10
10
0
0
10
% P
% Gln:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% R
% Ser:
19
10
10
19
19
0
10
10
10
10
10
10
10
10
10
% S
% Thr:
0
0
0
0
0
0
46
73
10
0
0
0
0
0
19
% T
% Val:
0
0
0
19
10
0
0
0
10
0
10
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _